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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS12 All Species: 25.45
Human Site: S134 Identified Species: 46.67
UniProt: Q96CB8 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CB8 NP_001135943.1 462 48808 S134 S S P I T V Q S S K D L P M A
Chimpanzee Pan troglodytes XP_517380 462 48786 S134 S S P I T V Q S S K D L P M A
Rhesus Macaque Macaca mulatta XP_001084188 462 48791 T134 S S P I T V Q T S K D L A M A
Dog Lupus familis XP_545012 788 84125 T460 S S P I T V Q T S K D L A M A
Cat Felis silvestris
Mouse Mus musculus Q9D168 461 48550 T133 S S P I T V Q T S K D L S M A
Rat Rattus norvegicus Q68FR3 461 48459 T133 S S P I T V Q T S K D L A M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511131 200 19036
Chicken Gallus gallus XP_420500 509 53231 T179 S S P I T V Q T S K D L S M P
Frog Xenopus laevis Q6DJM6 464 48894 L131 S S P V T V Q L S K D L P V P
Zebra Danio Brachydanio rerio Q6IQU7 479 49572 Q136 H S S P I A F Q T K D I P I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651507 328 34315 A22 V D P V L K K A I K L L H S S
Honey Bee Apis mellifera XP_393298 287 32118
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195035 333 36996 K27 G I A A K K P K I E P E V R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.9 54.9 N.A. 91.3 90.6 N.A. 29 73.2 67.4 60.1 N.A. 22.5 23.5 N.A. 25.1
Protein Similarity: 100 99.7 99.7 56.3 N.A. 95.8 95.4 N.A. 32.6 79.1 76.7 72.4 N.A. 39.3 37.4 N.A. 38.7
P-Site Identity: 100 100 86.6 86.6 N.A. 86.6 86.6 N.A. 0 80 73.3 26.6 N.A. 20 0 N.A. 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 0 86.6 86.6 46.6 N.A. 46.6 0 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 0 8 0 0 0 0 24 0 47 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 70 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 54 8 0 0 0 16 0 0 8 0 8 0 % I
% Lys: 0 0 0 0 8 16 8 8 0 77 0 0 0 0 0 % K
% Leu: 0 0 0 0 8 0 0 8 0 0 8 70 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 54 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 70 8 0 0 8 0 0 0 8 0 31 0 24 % P
% Gln: 0 0 0 0 0 0 62 8 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 62 70 8 0 0 0 0 16 62 0 0 0 16 8 8 % S
% Thr: 0 0 0 0 62 0 0 39 8 0 0 0 0 0 0 % T
% Val: 8 0 0 16 0 62 0 0 0 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _